Cyclotron Radiochemist – Quality Control

About the role

The Cyclotron Radiochemist (Quality Control) ensures the safety, efficacy, and quality of all radiopharmaceuticals produced at the hospital’s cyclotron facility, supporting advanced PET imaging services.

Key responsibilities

• Lead and perform comprehensive QC testing for radiopharmaceuticals, including radiochemical purity (HPLC, TLC), chemical purity, pH, radionuclidic identity (gamma‑ray spectrometry), and sterility.
• Manage the QC laboratory, maintain calibrated equipment, and ensure compliance with GMP principles and regulatory standards.
• Develop, validate, and implement new QC SOPs for novel radiotracers, supporting IND applications and clinical use.
• Support routine synthesis, purification, and QC of PET radiotracers using automated modules and coordinate production schedules.
• Ensure radiation safety, participate in audits, and contribute to research projects and scientific publications.

Required profile

• Master’s or PhD in Chemistry, Radiopharmaceutical Chemistry, Radiopharmacy or related field.
• 3‑5 years hands‑on experience in clinical or research radiopharmaceutical production, especially PET tracers.
• Demonstrated expertise in GMP‑compliant QC of radiopharmaceuticals and method development.
• Experience in a regulated laboratory with strong knowledge of analytical techniques.

Required skills

• High‑Performance Liquid Chromatography (HPLC)
• Thin‑Layer Chromatography (TLC)
• Gas Chromatography (GC)
• Gamma‑ray spectrometry
• Good Manufacturing Practice (GMP) compliance
• Radiopharmacy and radiochemistry techniques