Medical Laboratory Scientist - Stem Cell

About the role

The Medical Laboratory Scientist – Stem Cell will lead and optimise experiments in stem cell biology, cellular reprogramming, differentiation and regenerative medicine within the African Medical Centre of Excellence in Abuja.

Key responsibilities

• Design and execute stem cell research projects, including hypothesis development, protocol optimisation and timeline management.
• Perform advanced cell culture techniques, maintaining pluripotent and adult stem cell lines, and conduct cellular reprogramming using Yamanaka factors, episomal vectors or chemical methods.
• Differentiate stem cells into target cell types such as neurons, cardiomyocytes or hepatocytes and apply gene‑editing tools like CRISPR/Cas9 for functional studies.
• Run immunocytochemistry, flow cytometry and high‑throughput screening assays to assess cellular phenotypes and ensure data quality.
• Maintain laboratory compliance with GMP, FDA and HFEA standards, perform routine mycoplasma and contamination checks, and update SOPs and risk assessments.
• Collect, document and analyse experimental data using electronic lab notebooks, statistical software and bioinformatics tools for RNA‑seq and single‑cell sequencing.
• Collaborate with molecular biologists, bioinformaticians and clinicians, contribute to grant applications, manuscripts and conference presentations.
• Oversee inventory, equipment calibration and mentor junior scientists and technicians in stem cell techniques.

Required profile

• Bachelor’s degree in Microbiology, Medical Laboratory Science, Biology, Chemistry, Biochemistry or related field; Master’s degree is a plus.
• 1‑4 years of experience in a stem cell laboratory with progressive responsibility.
• Demonstrated expertise in stem cell isolation, culture, differentiation and characterisation.
• Proficiency in molecular biology methods such as PCR, flow cytometry and immunohistochemistry.
• Knowledge of ethical and regulatory requirements for stem cell research (GMP, FDA, HFEA).

Required skills

• Stem cell culture and differentiation techniques.
• Cellular reprogramming (Yamanaka factors, episomal vectors, chemical methods).
• CRISPR/Cas9 gene‑editing.
• Immunocytochemistry and immunohistochemistry.
• Flow cytometry and high‑throughput screening.
• Mycoplasma testing and contamination control.
• GMP and regulatory compliance.
• Electronic lab notebooks and data management.
• Statistical analysis and bioinformatics (RNA‑seq, single‑cell sequencing).